Biohacking for Longevity and Health

In today's fast-paced world, the quest for optimal health, longevity, and wellness is more important than ever. Drawing inspiration from a compelling conversation with Mark Young, a serial entrepreneur and CEO of Rise Agency and Zona Health, we delve into the transformative power of mindset, biohacking, and radical generosity. Mark's deep knowledge and passion for health and wellness offer profound insights that can help anyone improve their quality of life and embrace a healthier, more vibrant future.

Who is Mark Young?

Mark Young is not just a business leader; he is a visionary blending heart-centered leadership with business strategy. He is the author of Radical Generosity, a book aimed at empowering leaders to redefine success through giving rather than just gaining. His mission revolves around creating lasting impact through generosity, purpose, and vision. Mark’s work extends into revolutionizing cardiovascular wellness and scaling purpose-driven brands, making him a highly respected figure in the health and longevity space.

The Gathering: A Unique Approach to Health and Wellness

Currently attending a gathering in Phoenix, Arizona, Mark describes the event as a distinct departure from typical conferences. This gathering brings together 100 top health and wellness CEOs, founders, and executives, including luminaries like Dave Asprey and Cali Means. The atmosphere is not about hustling or selling but about genuine collaboration and impact. The group focuses on how to make a meaningful difference in the world through longevity, health, and entrepreneurship.

The Most Important Pillar of Longevity: Mindset

When asked about the biggest game-changer in health and longevity, Mark’s answer was clear and surprising: mindset. It’s not about the latest supplement, cold plunge, or sauna—though those are beneficial—but about the power of how we think.

"Whether you think you can or whether you think you can’t, you’re absolutely right." – Henry Ford

Mark emphasizes that negative thoughts and beliefs damage us at a cellular level. The body reacts physiologically to psychological trauma, creating a feedback loop that influences health outcomes. For instance, if we constantly tell ourselves that 65 is “old,” our bodies will start behaving as if they are old. Similarly, if someone believes they are diabetic or unhealthy, their body's cells respond accordingly, perpetuating illness.

Mark shared a vivid example of how a single word can trigger a fight-or-flight response in the nervous system, releasing chemicals like nitric oxide that affect cardiovascular function. This illustrates how our thoughts have immense power to influence our physical health.

How to Cultivate a Positive Mindset

So how do we improve our mindset? Mark’s approach combines rejecting negativity and actively seeking positivity. He doesn’t tolerate persistent negativity in his life and surrounds himself with aligned, supportive people.

Beyond simply avoiding negativity, Mark practices what he calls radical generosity. Giving—whether time, wisdom, or money—triggers the release of oxytocin, the "love hormone," which fosters feelings of connection and well-being. A meaningful hug, a kind message, or a small charitable act can literally rewire the brain and improve mood.

Mark shared personal examples of how he combats tough days by reaching out to friends, donating to charity, or creating joyful experiences. One story involved turning a disappointing canceled dinner into a fun, celebratory night with a friend, complete with champagne and laughter. This intentional shift in perspective is a powerful biohack for mental and emotional health.

Physical Activity and Other Biohacks

In addition to mindset and generosity, Mark highlights the importance of physical movement. When stressed or stuck in negative thoughts, he recommends going to the gym or engaging in exercise to release endorphins and dopamine, chemicals that boost mood and motivation.

This combination of mental and physical strategies forms a foundational approach to biohacking—using intentional practices to optimize one’s health and performance.

The Evolution of Mindset: From Hustle to Heart

Mark admits that his mindset has evolved over time. Raised with a traditional immigrant work ethic focused on grinding and hustling, he initially viewed networking and gatherings as a waste of time. However, exposure to like-minded individuals and positive environments shifted his perspective.

Now, Mark prioritizes being present in rooms filled with positive energy and opportunity for growth. He embraces ongoing learning and self-improvement, understanding that mindset is a constantly evolving journey.

Psychoneuroimmunology: Speaking to Your Cells

Mark is currently exploring psychoneuroimmunology, a discipline studying how the mind influences the immune system. He practices meditation and breathwork to communicate with his cells, encouraging healing and resilience.

Mark shared a remarkable personal story of healing, describing how he accidentally chopped off the tip of his finger and witnessed rapid, almost miraculous healing within two weeks. He attributes this to his intentional mindset and belief in the body's capacity to regenerate when properly supported.

The Food Crisis and the Make America Healthy Again Movement

Mark is deeply concerned about the state of food in America. He recently interviewed Dell Bigtree, a prominent advocate for food reform and health awareness. Together, they emphasize that this issue transcends politics, affecting all Americans regardless of party affiliation.

Key problems include:

• Processed and ultra-processed foods dominating the market

• Soil depletion leading to nutrient-poor crops

• Widespread use of pesticides and herbicides like glyphosate (Roundup)

• Artificial food dyes and fluoride in drinking water

• Rising rates of chronic illnesses, obesity, ADD, ADHD, and autism

Mark highlights disturbing statistics such as 80% of Americans being overweight or obese, 60-70% suffering chronic illnesses, and 45% diagnosed with hypertension. Meanwhile, 20% are taking GLP-1 agonists (weight loss medications) to combat metabolic issues.

He calls attention to the paradox where even the so-called "health food" aisles in grocery stores are filled with processed products rather than truly nourishing options.

Gut-Brain Connection and Addiction

Mark discusses recent research by Dr. Steven Gundry, who connects gut microbiome imbalances to addiction behaviors. The gut bacteria can influence cravings and mood, suggesting that healing the gut may be key to overcoming addictions and improving mental health.

Challenges and Practical Tips for Everyday Health

Mark acknowledges that perfect health is unattainable in today's world due to environmental toxins, EMFs, and processed food prevalence. However, he advocates for gradual progress and increased awareness.

Some practical steps he recommends include:

• Replacing plastic kitchen utensils with wood to reduce chemical exposure

• Filtering water and using filtered water for ice makers

• Removing mercury amalgam fillings with a biological dentist

• Engaging in regular meditation and breathwork

• Choosing nutrient-dense, minimally processed foods whenever possible

• Being mindful of environmental exposures and making incremental improvements

Mark stresses that health is a lifelong journey of continuous improvement rather than a destination.

Looking Ahead: The Future of Longevity and Health

Mark is excited about the future of health and longevity, especially as he approaches his 50th birthday. He is inspired by stories of individuals thriving well into their later decades, including his own father, who recently set a Guinness World Record in race car driving at age 68.

His philosophy is simple but powerful: mindset matters. Believing in the possibility of a vibrant, healthy life in your later years costs nothing but can yield immense benefits.

Final Thoughts: Radical Generosity and Making an Impact

Mark concludes by emphasizing the importance of showing up in the world with abundance and generosity. He encourages everyone to take small acts of kindness seriously, as these actions create physiological and psychological shifts that benefit both giver and receiver.

"How do we just show up in the world with a mindset of abundance rather than scarcity?"

Whether you are an entrepreneur, a health enthusiast, or simply someone seeking to improve your quality of life, Mark Young's insights offer a roadmap to better health and deeper fulfillment. By cultivating a positive mindset, engaging in thoughtful biohacks, and embracing generosity, we can all unlock greater longevity and impact.

For those inspired to explore further, Mark’s book Radical Generosity is a valuable resource. His work with Rise Agency and Zona Health continues to push the boundaries of cardiovascular wellness and purpose-driven business.

Remember, the journey to health and happiness is ongoing. Start with the next right step, embrace progress over perfection, and prioritize your mindset—it truly is the most powerful biohack you can master.

To reach Mark, visit his website and follow him on Instagram.

Watch this episode on YouTube.